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[四氯化碳中毒小鼠松果体和垂体退化的表现]

[Demonstration of pineal gland and pituitary involution in mice poisoned with carbon tetrachloride].

作者信息

Legait H, Hartemann P, Cunin B

出版信息

C R Seances Soc Biol Fil. 1978;172(2):289-92.

PMID:150919
Abstract

Ingestion of carbone tetrachloride by male C3H Orleans mice determines an involution of the pineal gland and of the hypophysis, as well as extensive lesions of the hepatic parenchyma. There may exist in these animals a higher blood-level of glucocorticoids, as this has been shown to be the case in men suffering from cirrhosis or hepatitis. Involution of the pineal gland in cases of stress, as has been shown by various authors, would result from an entirely different mechanism, that is by increased secretion of corticoadrenal hormones.

摘要

雄性C3H奥尔良小鼠摄入四氯化碳会导致松果体和垂体退化,以及肝实质的广泛损伤。这些动物体内可能存在较高水平的糖皮质激素,因为在肝硬化或肝炎患者中已证实存在这种情况。正如不同作者所表明的,应激情况下松果体的退化是由完全不同的机制导致的,即肾上腺皮质激素分泌增加。

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