Araki Y, Sakai N, Andoh T, Yoshimura S, Yamada H
Department of Neurosurgery, Gifu University School of Medicine, Japan.
Surg Neurol. 1992 Aug;38(2):141-5. doi: 10.1016/0090-3019(92)90092-2.
We report a case of central neurocytoma presenting with gigantism. The patient was a 19-year-old man with a 2-year history of rapid growth. Computed tomography revealed a round, slightly enhancing calcified tumor in the septal region. This lesion was resected, and postoperative radiotherapy was given. The preoperative serum growth hormone level was 20.7 ng/mL, and postoperatively this fell to 0.9 ng/mL. Pituitary dysfunction was not noted either before or after the operation. A low level of production of growth hormone releasing factor was detected when tumor cells obtained during surgery were cultured.
我们报告一例以巨人症为表现的中枢神经细胞瘤病例。患者为一名19岁男性，有2年快速生长病史。计算机断层扫描显示在中隔区域有一个圆形、轻度强化的钙化肿瘤。该病变被切除，并给予术后放疗。术前血清生长激素水平为20.7 ng/mL，术后降至0.9 ng/mL。手术前后均未发现垂体功能障碍。对手术中获取的肿瘤细胞进行培养时，检测到生长激素释放因子的低水平分泌。
