Daou Doumit, Coaguila Carlos, Benada Abdel, Razzouk Micheline, Haidar Mohamed, Colin Patrice, Lebtahi Rachida, Slama Michel, Guludec Domique Le
Department of Nuclear Medicine, Lariboisière University Hospital, Paris, France.
Nucl Med Commun. 2004 Mar;25(3):271-6. doi: 10.1097/00006231-200403000-00010.
Electrocardiographically gated blood pool SPECT (GBPS) is an interesting method for measuring left ventricular (LV) ejection fraction (LVEF) and volume. Recently, the availability of completely automatic GBPS processing software has been reported. We aimed to evaluate its reliability in measuring global LV systolic function. In addition, using the same population, we compared its reliability to that of three previously reported methods for processing GBPS.
We studied the performances of the new GBPS system for the evaluation of LVEFs and volumes in 29 patients. The LVEF provided by the planar equilibrium radionuclide angiography (planarLAO) and LV volumes provided by radiological LV contrast angiography (X-rays) were used as 'gold standards'.
The new GBPS system failed in one patient. It shows good reproducibility for the measurement of both LVEF and volume. LVEF provided by this system is moderately correlated to planarLAO (r = 0.62; P < 0.001). The new GBPS constantly overestimates LVEF (P < 0.05). Results for LV volumes are moderately correlated to those obtained by X-ray investigation (r = 0.7; P < 0.001) but are significantly lower (P < 0.0001). There is a linear correlation between the average and the paired absolute difference for LV volumes (r = 0.52, P = 0.0001).
The new, completely automatic, GBPS processing software is an interesting, moderately reliable method for measuring LVEF and volume. The performance of the method is lower than that previously reported for the same population for the other three GBPS processing methods.
心电图门控血池单光子发射计算机断层扫描（GBPS）是一种用于测量左心室（LV）射血分数（LVEF）和容积的有趣方法。最近，有报道称出现了完全自动的GBPS处理软件。我们旨在评估其在测量整体左心室收缩功能方面的可靠性。此外，我们使用同一人群，将其可靠性与之前报道的三种GBPS处理方法进行比较。
我们研究了新的GBPS系统在29例患者中评估LVEF和容积的性能。将平面平衡放射性核素血管造影（平面LAO）提供的LVEF和放射学左心室造影（X线）提供的左心室容积用作“金标准”。
新的GBPS系统在1例患者中出现故障。它在测量LVEF和容积方面显示出良好的可重复性。该系统提供的LVEF与平面LAO呈中度相关（r = 0.62；P < 0.001）。新的GBPS持续高估LVEF（P < 0.05）。左心室容积的结果与通过X线检查获得的结果呈中度相关（r = 0.7；P < 0.001），但明显更低（P < 0.
