Abe Takashi, Ogawa Keiko, Nittono Hiroshi, Hori Tadao
Department of Behavioral Sciences, Faculty of Integrated Arts and Sciences, Hiroshima University, 1-7-1 Kagamiyama, Higashi-Hiroshima, 739-8521 Japan.
Neuroreport. 2004 Mar 22;15(4):735-8. doi: 10.1097/00001756-200403220-00033.
Differences between oculomotor control of rapid eye movements (REMs) in REM sleep and that of saccades in wakefulness were examined electrophysiologically in human adults. Fourteen healthy young volunteers participated in the study. Brain potentials were recorded from the scalp and time-locked to the onsets of saccades and REMs during a visually triggered saccade task and natural nocturnal sleep. In wakefulness, presaccadic positivity (PSP) appeared at centro-parietal sites starting about 150 ms before saccades. In REM sleep, no PSP was found but a slow negative potential (pre-REM negativity: PRN) appeared at the prefrontal sites. The findings suggest that the generation of REMs does not involve the cortical process reflected in the PSP but is associated with a different neural process reflected in the PRN.
在成年人类中，通过电生理学方法研究了快速眼动睡眠（REM）中快速眼动（REMs）的眼球运动控制与清醒时扫视运动控制之间的差异。14名健康的年轻志愿者参与了这项研究。在视觉触发扫视任务和自然夜间睡眠期间，从头皮记录脑电信号，并将其与扫视和快速眼动的起始时间锁定。在清醒状态下，扫视前正电位（PSP）出现在中央顶叶部位，大约在扫视前150毫秒开始出现。在快速眼动睡眠中，未发现PSP，但在前额叶部位出现了一个缓慢的负电位（快速眼动前负电位：PRN）。这些发现表明，快速眼动的产生不涉及PSP所反映的皮质过程，而是与PRN所反映的不同神经过程相关。
