Dobloug J H
Infeksjonsmedisinsk avdeling, Ullevål sykehus, Oslo.
Tidsskr Nor Laegeforen. 1992 Jun 10;112(15):1961-3.
Fluconazole (Diflucan) is a new triazole antifungal agent that is effective against a wide range of fungi and has a favourable pharmacokinetic profile. Fluconazole is absorbed well after oral intake independent of food intake. Fluconazole is given once daily, in a dose of 50-400 mg. The dosage is the same for oral and parenteral administration. Tissue penetration is good, as is the concentration in cerebrospinal fluid. Fluconazole should not be given to children under 16 years of age, nor to pregnant or breast-feeding women. In Norway, fluconazole is indicated for treatment of candida vaginitis that is resistant to other treatment, invasive candida infection, candida stomatitis in immunocompromised hosts, and cryptococcal meningitis.
氟康唑（大扶康）是一种新型三唑类抗真菌药物，对多种真菌有效，且具有良好的药代动力学特征。口服氟康唑后吸收良好，不受进食影响。氟康唑每日给药一次，剂量为50 - 400毫克。口服和胃肠外给药的剂量相同。组织穿透力良好，脑脊液中的浓度也较高。16岁以下儿童、孕妇或哺乳期妇女不应使用氟康唑。在挪威，氟康唑适用于治疗对其他治疗耐药的念珠菌性阴道炎、侵袭性念珠菌感染、免疫功能低下宿主的念珠菌性口腔炎以及隐球菌性脑膜炎。
