Mathieu Marie-Christine
Histopathologie B, Institut Gustave-Roussy, 39 rue Camille Desmoulins, 94805 Villejuif.
Ann Pathol. 2003 Dec;23(6):508-17.
The development of the sentinel node concept has led to the selective excision of this node as an alternative to complete axillary dissection. When the sentinel node is negative, axillary dissection can be avoided. Accurate assessment of the sentinel node is an crucial part of the technique, but there is currently no consensus regarding the method of analysis. The localization of the sentinel node, the intra-operative analysis, the pathological analysis and immunohistochemistry are reviewed. An increase in the number of micrometastases detected in the sentinel node has led to the modification of the pN in the pTNM classification in 2003. In the future, the selection of patients in whom axillary dissection must be performed could be improved by identifying predictive factors for axillary involvement.
前哨淋巴结概念的发展促使人们选择切除该淋巴结，以替代完全腋窝清扫术。当前哨淋巴结为阴性时，可避免腋窝清扫术。准确评估前哨淋巴结是该技术的关键部分，但目前对于分析方法尚无共识。本文对前哨淋巴结的定位、术中分析、病理分析及免疫组化进行了综述。2003年，前哨淋巴结中检测到的微转移灶数量增加，导致pTNM分类中pN的修订。未来，通过识别腋窝受累的预测因素，可改善必须进行腋窝清扫术患者的选择。
