Huang Tung-Fu, Perry Stephanie M, Soslowsky Louis J
McKay Orthopaedic Research Laboratory, University of Pennsylvania, Philadelphia, PA 19104-6081, USA.
Ann Biomed Eng. 2004 Mar;32(3):336-41. doi: 10.1023/b:abme.0000017537.26426.76.
Musculoskeletal soft tissue injuries from athletic activities are common in the rotator cuff tendons, lateral epicondyle of the elbow, the patella tendon, and the Achilles tendon. Despite the fact that the Achilles tendon is the largest and strongest tendon in the human body, it is frequently injured in the athletic setting. To study the etiology and pathogenesis of Achilles tendon injuries, our goal was to develop a model of Achilles tendon overuse by evaluating the Achilles tendons from animals subjected to the exercise protocol previously described as overuse for the supraspinatus tendon. We hypothesized that the same exercise protocol would produce injuries to the Achilles tendon as demonstrated by changes in the cross-sectional area and biomechanical properties. While a significant injury was induced into the supraspinatus tendon, we found no changes in the Achilles tendons of these exercised animals based on gross observation, geometric measurements, and mechanical testing analyses. Although surprising, there are many possible explanations for these findings including differences in potential injury mechanisms, functional capabilities of the differing tendons, and other factors.
运动活动导致的肌肉骨骼软组织损伤在肩袖肌腱、肘部外侧髁、髌腱和跟腱中很常见。尽管跟腱是人体最大、最强壮的肌腱，但它在运动环境中经常受伤。为了研究跟腱损伤的病因和发病机制，我们的目标是通过评估接受先前描述为对冈上肌腱过度使用的运动方案的动物的跟腱，建立一个跟腱过度使用的模型。我们假设相同的运动方案会导致跟腱损伤，如横截面积和生物力学特性的变化所示。虽然冈上肌腱受到了严重损伤，但基于大体观察、几何测量和力学测试分析，我们发现这些运动动物的跟腱没有变化。尽管这些发现令人惊讶，但对其有许多可能的解释，包括潜在损伤机制的差异、不同肌腱的功能能力以及其他因素。
