Schumacher H. Christian, Khaw Alexander V., Meyers Philip M., Gupta Rishi, Higashida Randall T.
Neuroendovascular Service, Departments of Radiology and Neurological Surgery, Columbia and Cornell University Medical Centers, Neurological Institute.
Curr Treat Options Cardiovasc Med. 2004 Jun;6(3):193-198. doi: 10.1007/s11936-996-0013-y.
Depending on the population studied, intracranial atherosclerosis accounts for 10% to 29% of ischemic brain events. A significant number of patients with intracranial atherosclerosis continue to suffer from repeated strokes or transient ischemic attacks despite optimal medical management. In selected patients, intracranial angioplasty with or without stenting is a promising treatment option. Patient selection, careful periprocedural medical management, and a highly skilled neuroendovascular interventionalist are required in order to perform the procedure with an acceptable risk.
根据所研究的人群,颅内动脉粥样硬化占缺血性脑事件的10%至29%。尽管进行了最佳的药物治疗,但仍有相当数量的颅内动脉粥样硬化患者继续遭受反复中风或短暂性脑缺血发作。对于选定的患者,颅内血管成形术(无论是否置入支架)是一种有前景的治疗选择。为了在可接受的风险下进行该手术,需要进行患者选择、仔细的围手术期药物管理以及技术高超的神经血管介入专家。