Lauer K, Firnhaber W
Neurologischen Klinik Städtischen Kliniken Darmstadt.
Versicherungsmedizin. 1992 Aug 1;44(4):125-30.
Epidemiology plays a prominent role in the search for environmental risk factors in multiple sclerosis (MS). The basic pattern with the predilection for temperate zones of the globe, whites, females and medium age groups was confirmed throughout. Whether or not MS is increasing in frequency is highly debated. Although no clear risk factors have been demonstrated so far, a certain association of the MS risk with the factors "low temperatures and precipitation", "consumption of animal proteins/fats or meat", "familiar occurrence of MS" and with a late occurrence of common childhood infections became obvious. Many other putative risk factors were not confirmed in most studies.
流行病学在寻找多发性硬化症(MS)的环境风险因素方面发挥着重要作用。全球温带地区、白人、女性和中年人群的基本患病模式已得到全面证实。MS的发病率是否正在上升存在激烈争论。尽管目前尚未证实明确的风险因素,但MS风险与“低温和降水”、“动物蛋白/脂肪或肉类的摄入”、“家族性MS发病”以及儿童期常见感染的较晚发生之间存在一定关联已变得明显。在大多数研究中,许多其他假定的风险因素未得到证实。