线粒体ADP、ATP转位酶的生物合成。
The biosynthesis of the mitochondrial ADP, ATP translocator.
作者信息
Hackenberg H, Riccio P, Klingenberg M
出版信息
Eur J Biochem. 1978 Aug 1;88(2):373-8. doi: 10.1111/j.1432-1033.1978.tb12458.x.
Abstract
The biosynthesis of the ADP,ATP carrier was studied in mitochondria of Neurospora crassa. The carrier was isolated as the carboxyatractylate-protein complex and characterized in dodecylsulphate/polyacrylamide gel electrophoresis to have a Mr = 33 000. Applying the inhibitors chloramphenicol for the intramitochondrial translation and cycloheximide for extramitochondrial translation, the site of synthesis of this polypeptide was found to be extramitochondrially located.
摘要
在粗糙脉孢菌的线粒体中研究了ADP、ATP载体的生物合成。该载体作为羧基苍术苷 - 蛋白质复合物被分离出来，并在十二烷基硫酸盐/聚丙烯酰胺凝胶电泳中鉴定出其分子量为33000。应用氯霉素抑制线粒体内翻译，应用环己酰亚胺抑制线粒体外翻译，发现该多肽的合成位点位于线粒体外。
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