Wagner S, Meran J G, Manns M
Abteilung für Gastroenterologie und Hepatologie, Medizinischen Hochschule Hannover, Deutschland.
Wien Med Wochenschr. 1992;142(8-9):162-6.
Antral gastritis and peptic ulcer disease are closely related to gastric Helicobacter pylori (HP) infection. HP possesses several pathogenic features which point to a causal role of HP in the development of gastroduodenal lesions. It is now generally accepted that HP causes type B gastritis, while its role in the pathogenesis of peptic ulcers is still unsolved. According to the classical ulcer concept, peptic ulceration is the result of an imbalance between protective mucosal mechanisms and aggressive digestive factors. The identification of HP does not disprove this concept, however, HP has to be added as a major pathogenic factor.
胃窦炎和消化性溃疡病与胃幽门螺杆菌（HP）感染密切相关。HP具有多种致病特性，表明其在胃十二指肠病变发展中起因果作用。目前普遍认为HP可导致B型胃炎，但其在消化性溃疡发病机制中的作用仍未明确。根据经典的溃疡概念，消化性溃疡是保护性黏膜机制与侵袭性消化因子失衡的结果。然而，HP的发现并未否定这一概念，不过，HP必须被视为一个主要的致病因素。
