Hief C, Frohner K, Podczeck A, Kaltenbrunner W, Nürnberg M, Steinbach K
Ludwig-Boltzmann-Institut für Arrhythmieforschung, 3. Medizinische Abteilung, Wilhelminenspital, Wien.
Z Kardiol. 1992 Jul;81(7):385-8.
The significance of provocative tests in patients with bifascicular block is not established. We studied 14 patients with bifascicular block, syncope and documented episodes of high degree AV-block. 1.5 mg/kg Diprafenon was given after a period of at last 12 hours 1:1 AV-conduction. Electrophysiologic evaluation was performed before and after diprafenon. AV-block III could be provoked in 1 of 14 patients with Diprafenon. Therefore a total AV block occurred in 7% of patients. The low sensitivity of provocative test with Diprafenon even in patients with documented high degree AV-block prevents its application in clinical practice.
双分支阻滞患者中激发试验的意义尚未明确。我们研究了14例双分支阻滞、晕厥且有高度房室传导阻滞发作记录的患者。在至少12小时的1:1房室传导后给予1.5mg/kg双苯丙胺。在给予双苯丙胺前后进行电生理评估。14例患者中有1例使用双苯丙胺可诱发三度房室传导阻滞。因此，7%的患者发生了完全性房室传导阻滞。即使在有高度房室传导阻滞记录的患者中，双苯丙胺激发试验的低敏感性也使其无法应用于临床实践。
