Henriksson Karin M, Lindblad Ulf, Agren Bo, Nilsson-Ehle Peter, Råstam Lennart
Department of Community Medicine, (Malmö) Lund University, Sweden.
Scand J Public Health. 2003;31(4):305-11. doi: 10.1080/14034940210164948.
To investigate associations between CVD risk factors and socio-economic status (SES) in middle-age men during a period of economic changes.
Crossectional surveys at age 37, 40 and 43 in a birth cohort of men in Helsingborg, Sweden. All male residents born 1953-4 (n = 1460) were invited; participation rates were 68% (n = 991) at baseline. Of these enrolled, 78% (n = 770) were re-examined after three years and 71% (n = 702) again after six years follow-up. Main outcome measures were body mass index (BMI), S-cholesterol, HDL-cholesterol, systolic and diastolic blood pressure (SBP, DBP), smoking and leisure time physical activity (LTPA), education, employment, ethnicity.
Baseline unemployment rate was low, n = 23 (2.4%), but three and six years later it had increased to 61 (8.2%) and 51 (7.5%) respectively. At baseline, BMI and S-cholesterol were significantly higher in unemployed than in employed men (deltaBMI 1.6 kg/m2, CI: 0.2; 2.9, delta S-cholesterol 0.6 mmol/L, CI: 0.1; 1.0), and in men with short versus long education (delta BMI 0.9 kg/m2, CI: 0.4; 1.4, delta S-cholesterol 0.2 mmol/L, CI: 0.03: 0.4), independent of other SES factors. Over the study period crossectional associations with employment status disappeared for BMI, but remained between short education and BMI. Short education was also associated with a significant increase in BMI (delta = 0.4 kg/m2, CI: 0.1; 0.7) during 6-year follow-up.
This study shows that associations between unemployment and CVD risk factors were lost when unemployment rates increased. When the attributable risk of unemployment associated with CVD risk factors is estimated, it is vital to consider the general unemployment rates in society.
调查经济变革时期中年男性心血管疾病(CVD)风险因素与社会经济地位(SES)之间的关联。
对瑞典赫尔辛堡一个男性出生队列在37岁、40岁和43岁时进行横断面调查。邀请了所有1953 - 1954年出生的男性居民(n = 1460);基线时参与率为68%(n = 991)。在这些被纳入研究的人群中,78%(n = 770)在三年后接受了复查,71%(n = 702)在六年随访后再次接受检查。主要观察指标包括体重指数(BMI)、总胆固醇、高密度脂蛋白胆固醇、收缩压和舒张压(SBP、DBP)、吸烟和休闲时间体力活动(LTPA)、教育程度、就业情况、种族。
基线时失业率较低,n = 23(2.4%),但三年和六年后分别升至61(8.2%)和51(7.5%)。在基线时,失业男性的BMI和总胆固醇显著高于就业男性(BMI差值1.6 kg/m²,CI:0.2;2.9,总胆固醇差值0.6 mmol/L,CI:0.1;1.0),且在教育年限短与长的男性中也存在差异(BMI差值0.9 kg/m²,CI:0.4;1.4,总胆固醇差值0.2 mmol/L,CI:0.03;0.4),不受其他社会经济地位因素影响。在研究期间,BMI与就业状况的横断面关联消失,但教育年限短与BMI之间的关联仍然存在。教育年限短还与六年随访期间BMI显著增加(差值 = 0.4 kg/m²,CI:0.1;0.7)有关。
本研究表明,当失业率上升时,失业与心血管疾病风险因素之间的关联消失。在估计与心血管疾病风险因素相关的失业归因风险时,考虑社会总体失业率至关重要。