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横行腹直肌肌皮瓣乳房重建术:肿胀技术可减少失血及输血需求。

TRAM flap breast reconstruction: tumescent technique reduces blood loss and transfusion requirement.

作者信息

Paige Keith T, Bostwick John, Bried Jean Timble

机构信息

Emory Plastic Surgery, Emory University, Atlanta, GA, USA.

出版信息

Plast Reconstr Surg. 2004 May;113(6):1645-9. doi: 10.1097/01.prs.0000117195.00724.27.

Abstract

The tumescent technique has been shown to be efficacious in reducing both operative and postoperative bleeding without significant deleterious side effects in suction lipectomy. In this study, the effects of the tumescent technique on postoperative complications in transverse rectus abdominis myocutaneous (TRAM) flap breast reconstruction are investigated. All women who underwent a TRAM flap breast reconstruction by the senior author (J.B.) at the Emory Clinic during the years 1990 to 1996 were pooled (n = 386). Any woman who had a preincision infiltration of 0.25% epinephrine-containing saline solution (>200 cc) around the donor site was included in the tumescent group (n = 59). Medical records were reviewed, and rates of partial flap loss, fat necrosis (> or =10 percent flap volume), flap full-thickness skin loss, donor-site complication (skin loss, hernia, or infection), and blood transfusion were determined. Group rates were compared. The infiltrated group had a significantly lower transfusion rate as compared with the control group (0.34 units versus 1.32 units, p < 0.001). The rates of partial flap loss and fat necrosis were less in the tumescent group, but not significantly (0 percent versus 4 percent, p = 0.232; and 1.7 percent versus 10.4 percent, p = 0.058). There were no significant differences in the incidence of full-thickness skin loss or donor-site complications. Donor-site infiltration before incision with a 0.25% epinephrine-containing saline solution significantly reduced the transfusion requirement in TRAM flap breast reconstruction patients without adversely affecting either breast mound or abdominal donor-site complication rates.

摘要

肿胀技术已被证明在抽脂术中能有效减少术中及术后出血,且无明显有害副作用。在本研究中,探讨了肿胀技术对横行腹直肌肌皮瓣(TRAM)乳房重建术后并发症的影响。将1990年至1996年期间在埃默里诊所由资深作者(J.B.)进行TRAM瓣乳房重建的所有女性纳入研究(n = 386)。供区周围术前浸润含0.25%肾上腺素盐水溶液(>200 cc)的任何女性被纳入肿胀组(n = 59)。回顾医疗记录,确定部分皮瓣丢失、脂肪坏死(皮瓣体积≥10%)、皮瓣全层皮肤丢失、供区并发症(皮肤丢失、疝气或感染)及输血的发生率,并比较两组发生率。与对照组相比,浸润组的输血率显著降低(0.34单位对1.32单位,p < 0.001)。肿胀组的部分皮瓣丢失率和脂肪坏死率较低,但无显著差异(0%对4%,p = 0.232;1.7%对10.4%,p = 0.058)。全层皮肤丢失或供区并发症的发生率无显著差异。术前在供区浸润含0.25%肾上腺素的盐水溶液可显著降低TRAM瓣乳房重建患者的输血需求,且对乳房隆起或腹部供区并发症发生率无不利影响。

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