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警报疗法对单纯性夜间遗尿症患儿膀胱功能容量的影响。

The effect of alarm treatment on the functional bladder capacity in children with monosymptomatic nocturnal enuresis.

作者信息

Hvistendahl G M, Kamperis K, Rawashdeh Y F, Rittig S, Djurhuus J C

机构信息

International Enuresis Research Center, Institute of Experimental Clinical Research, Skejby Hospital, Aarhus, Denmark.

出版信息

J Urol. 2004 Jun;171(6 Pt 2):2611-4. doi: 10.1097/01.ju.0000110762.45940.fa.

Abstract

PURPOSE

We studied the characteristics of a group of monosymptomatic nocturnal enuretics successfully treated with the alarm system, with special reference to changes in functional bladder capacity.

MATERIALS AND METHODS

The diaries of 7 girls and 19 boys 7 to 13 years old with severe nocturnal enuresis, small daytime bladder capacity (70% or less of expected capacity for age) and poor or absent response to desmopressin were analyzed. Patients were treated with an alarm until complete dryness was achieved for 21 consecutive nights before ending therapy. Immediately after the treatment they recorded a 1-week followup diary of voiding and fluid intake.

RESULTS

Mean duration of the alarm treatment was 82 days, and there was no change in nocturnal or 24-hour diuresis from baseline to followup. Nocturia developed during the alarm treatment in 48% of the children. The nocturnal diuresis on nocturia nights was significantly higher than on nights without nocturia. Daytime functional bladder capacity increased significantly in children with and without nocturia.

CONCLUSIONS

Treatment with an alarm system increases daytime functional bladder capacity significantly in children with and without nocturia. A higher nocturnal urine production on nocturia nights explains why some children have nocturia and others do not.

摘要

目的

我们研究了一组使用警报系统成功治疗的单症状夜间遗尿症患者的特征,特别关注功能性膀胱容量的变化。

材料与方法

分析了7名7至13岁患有严重夜间遗尿症、日间膀胱容量小(为年龄预期容量的70%或更低)且对去氨加压素反应不佳或无反应的女孩和19名男孩的日记。患者接受警报治疗,直至连续21个晚上完全干爽后结束治疗。治疗结束后,他们立即记录了1周的排尿和液体摄入随访日记。

结果

警报治疗的平均持续时间为82天,从基线到随访,夜间或24小时尿量没有变化。48%的儿童在警报治疗期间出现夜尿症。夜尿症夜晚的夜间尿量显著高于无夜尿症的夜晚。有夜尿症和无夜尿症的儿童日间功能性膀胱容量均显著增加。

结论

警报系统治疗可使有夜尿症和无夜尿症的儿童日间功能性膀胱容量均显著增加。夜尿症夜晚较高的夜间尿量解释了为什么有些儿童有夜尿症而有些儿童没有。

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