Fedele Luigi, Bianchi Stefano, Zanconato Giovanni, Bettoni Gaia, Gotsch Francesca
Clinica Ostetrico-Ginecologica dell' Università di Milano, Ospedale San Paolo, Milan, Italy.
Am J Obstet Gynecol. 2004 Apr;190(4):1020-4. doi: 10.1016/j.ajog.2003.10.698.
The purpose of this study was to evaluate long-term results in patients who received conservative surgical treatment for rectovaginal endometriosis.
We analyzed the follow-up data for 83 women who underwent surgery for rectovaginal endometriosis. The inclusion criteria were age 20 to 42 years, moderate-to-severe pain symptoms, conservative treatment with retention of the uterus, and at least 1 ovary; the follow-up period was > or =12 months. Kaplan-Meier analysis and Cox regression were used to calculate recurrence rates.
The cumulative rates of pain recurrence, clinical or sonographic recurrence, and new treatment were 28%, 34%, and 27%, respectively. The younger patients had the higher risk of recurrence. Pregnancy had protective effects against the recurrence of symptoms and a need for a new treatment. Patients who underwent bowel resection had fewer recurrences.
Segmental resection and anastomosis of the bowel, when necessary, improves the outcome without affecting chances of conception. Higher recurrence rates in younger patients seems to justify a more radical treatment in this group of women.
本研究旨在评估接受直肠阴道子宫内膜异位症保守性手术治疗患者的长期疗效。
我们分析了83例行直肠阴道子宫内膜异位症手术的女性患者的随访数据。纳入标准为年龄20至42岁、中重度疼痛症状、保留子宫及至少1个卵巢的保守治疗,随访期≥12个月。采用Kaplan-Meier分析和Cox回归计算复发率。
疼痛复发、临床或超声复发以及新治疗的累积发生率分别为28%、34%和27%。年轻患者复发风险更高。妊娠对症状复发和新治疗需求具有保护作用。接受肠切除术的患者复发较少。
必要时行肠段切除吻合术可改善预后,且不影响受孕机会。年轻患者较高的复发率似乎表明该组女性需要更积极的治疗。