Horváth Géza, Tóth Csaba, Szentgyörgyi Lajos, Szerafin Tamás, Flaskó Tibor, Péterffy Arpád
Debreceni Egyetem Orvos- és Egészségtudományi Centrum, Szívsebészeti Klinika.
Magy Seb. 2003 Dec;56(6):239-41.
Invading the inferior vena cava and right atrium is the most serious, but fortunately not common complication of renal cell carcinoma. Radical nephrectomy with tumor-thrombus extraction is the only way to improve these patients survival. Cardiopulmonary bypass with or without deep hypothermia and total circulatory arrest might be necessary during surgery. Between 1998 and 2003 at the Department of Cardiac Surgery of University of Debrecen, 5 patients, with renal cell carcinoma extending into the right atrium, had radical nephrectomy and thrombectomy. We used cardiopulmonary bypass, in 2 patients in total circulatory arrest, in deep hypothermia. There was no operative death and neurological complications. One patient died 3 years after the operation due to cardiac failure. In average 42 months after surgery, 4 surviving patients are under regular follow up, they have a good quality of life, without recurrence. In our opinion cardiopulmonary bypass and total circulatory arrest, if necessary, gives the best way for surgical resection of renal cell carcinoma extending into the right atrium.
侵犯下腔静脉和右心房是肾细胞癌最严重的并发症,但幸运的是并不常见。根治性肾切除术联合肿瘤血栓切除术是提高这些患者生存率的唯一方法。手术期间可能需要进行体外循环,可伴有或不伴有深度低温和完全循环停止。1998年至2003年间,在德布勒森大学心脏外科,5例肾细胞癌侵犯右心房的患者接受了根治性肾切除术和血栓切除术。我们采用了体外循环,2例患者在深度低温下进行了完全循环停止。无手术死亡和神经并发症。1例患者术后3年因心力衰竭死亡。术后平均42个月,4例存活患者接受定期随访,生活质量良好,无复发。我们认为,必要时体外循环和完全循环停止为侵犯右心房的肾细胞癌手术切除提供了最佳途径。