Sharp Richard R, Foster Morris W
Program in Environmental Health Policy and Ethics, National Institute of Environmental Health Sciences, USA.
Jurimetrics. 2002 Winter;42(2):165-86.
American Indian and Alaskan Native communities have expressed concern about the use of human biological materials in research. These concerns have prompted research sponsors and professional organizations to develop guidelines for investigators working with these communities. This paper reviews research guidelines and presents recommendations that reflect "best practices" for working with North American indigenous communities in the collection, storage, and distribution of human biological materials for research. These recommendations strike a reasonable balance between three imperatives in research: (1) minimizing harm, (2) treating sample contributors with respect, and (3) promoting intellectual freedom to pursue a range of research questions. The recommendations can be used in designing appropriate methods of collecting and using human biological materials from members of American Indian and Alaskan Native communities and will likely be applicable to other historically disadvantaged communities as well.
美国印第安人和阿拉斯加原住民社区对研究中使用人类生物材料表示担忧。这些担忧促使研究资助者和专业组织为与这些社区合作的研究人员制定指导方针。本文回顾了研究指导方针，并提出了一些建议，这些建议反映了在为研究收集、储存和分发人类生物材料时与北美原住民社区合作的“最佳实践”。这些建议在研究的三个要素之间达成了合理平衡：（1）将危害降至最低；（2）尊重样本提供者；（3）促进追求一系列研究问题的学术自由。这些建议可用于设计从美国印第安人和阿拉斯加原住民社区成员中收集和使用人类生物材料的适当方法，并且可能也适用于其他历史上处于弱势的社区。
