Lee Euni, McNally Diane L, Zuckerman Ilene H
Center for Minority Health Services Research, Department of Clinical and Administrative Pharmacy Sciences, School of Pharmacy, Howard University, 2300 Fourth Street NW, Washington, DC 20059-0001, USA.
Ann Pharmacother. 2004 Jun;38(6):961-6. doi: 10.1345/aph.1D515. Epub 2004 Apr 30.
The 1990 Omnibus Budget Reconciliation Act mandated drug utilization review in response to inappropriate drug use. In the Pennsylvania Medicaid program, pediatric asthma is associated with high healthcare utilization and cost.
To determine the effects of a physician-focused educational intervention on asthma drug use and healthcare utilization.
Pre- and postintervention comparison design was used in children 5-18 years of age who were enrolled in the Pennsylvania Medicaid fee-for-service program from July 1, 1998, to March 31, 1999 (preintervention), and July 1, 1999, to March 31, 2000 (postintervention). The intervention packet included patients' drug profiles, medical history, monograph with national asthma management guidelines, and patient education materials to physicians. Main outcome measures are changes in asthma drug utilization among high-users of short-acting beta(2)-agonists (SAB).
The intervention focused on 2 asthma drug use criteria: (1) high-use of quick-relief medication and (2) use of salmeterol without the availability of a quick-relief medication. The intervention reduced quick-relief medication use by 26% among patients with higher use without significant changes in long-term control drugs. In addition, 82% of the recipients evaluated had a positive change in salmeterol utilization as either having an SAB inhaler added after the intervention or salmeterol discontinued after the intervention. There was no significant change in asthma-related emergency department visits or hospitalizations.
Although the physician responders agreed on the usefulness of the educational materials, the results suggest that the intervention had limited success in improving the pharmacologic management and no effect on the health outcomes. We believe that mailed educational materials to physicians can be effective to change prescribing behavior; however, a more multifaceted intervention may be necessary to improve health outcomes.
1990年《综合预算协调法案》要求进行药物使用审查,以应对不当用药情况。在宾夕法尼亚州的医疗补助计划中,儿童哮喘与高医疗利用率和高成本相关。
确定以医生为重点的教育干预对哮喘药物使用和医疗利用率的影响。
采用干预前后对比设计,研究对象为1998年7月1日至1999年3月31日(干预前)以及1999年7月1日至2000年3月31日(干预后)参加宾夕法尼亚州医疗补助按服务收费计划的5至18岁儿童。干预资料包包括患者的用药记录、病史、附有国家哮喘管理指南的专著以及给医生的患者教育材料。主要结局指标是短效β₂激动剂(SAB)高用量使用者中哮喘药物使用情况的变化。
干预聚焦于两条哮喘药物使用标准:(1)快速缓解药物高用量;(2)使用沙美特罗但未配备快速缓解药物。干预使高用量患者的快速缓解药物使用量减少了26%,而长期控制药物使用量无显著变化。此外,82%接受评估的受试者在沙美特罗使用方面有积极变化,即在干预后添加了SAB吸入器或停用了沙美特罗。哮喘相关的急诊科就诊次数或住院次数无显著变化。
尽管医生反馈者认可教育材料的有用性,但结果表明该干预在改善药物管理方面成效有限,且对健康结局无影响。我们认为向医生邮寄教育材料可有效改变处方行为;然而,可能需要更全面的干预措施来改善健康结局。