Dormans John P, Hanna B Guirguis, Johnston Douglas R, Khurana Jasvir S
Division of Orthopaedic Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Clin Orthop Relat Res. 2004 Apr(421):205-11. doi: 10.1097/01.blo.0000126336.46604.e1.
High recurrence rates have been reported after surgical treatment of aneurysmal bone cysts, ranging from 10-59%, and greater (five of seven) in children younger than 10 years. No previous study has focused specifically on recurrence as a function of age in a large pediatric study. The purpose of the current study was to review the outcome of current surgical techniques in the treatment of primary aneurysmal bone cysts in children and to determine if recurrence rates were higher in younger children, as proposed by some authors. This study included 45 children with primary aneurysmal bone cysts with more than 2 years followup after their first treatment using our current four-step surgical technique. The subjects were studied and classified on the basis of their age group (< or = 10 years of age or >10 years of age). The recurrence rate, and other parameters were determined after surgical treatment. Of the 45 children with primary aneurysmal bone cysts, 13 children were 10 years or younger and 32 were older than 10 years. Persistence or recurrence of the lesion requiring additional surgery occurred in three children in the younger age group and in five children in the older age group. The difference in persistence or recurrence rates based on age was not statistically significant. However, the persistence or recurrence rates are lower than previously reported (82% overall success rate after initial surgery).
据报道,动脉瘤性骨囊肿手术治疗后的复发率较高,范围在10%-59%,10岁以下儿童的复发率更高(7例中有5例)。此前尚无大型儿科研究专门关注复发与年龄的关系。本研究的目的是回顾当前手术技术治疗儿童原发性动脉瘤性骨囊肿的结果,并确定复发率是否如一些作者所提出的那样在年幼儿童中更高。本研究纳入了45例原发性动脉瘤性骨囊肿患儿,他们在首次采用我们目前的四步手术技术治疗后进行了超过2年的随访。根据年龄组(≤10岁或>10岁)对研究对象进行研究和分类。在手术治疗后确定复发率及其他参数。在45例原发性动脉瘤性骨囊肿患儿中,13例年龄在10岁及以下,32例年龄大于10岁。年龄较小的组中有3例患儿病变持续存在或复发需要再次手术,年龄较大的组中有5例。基于年龄的病变持续存在或复发率差异无统计学意义。然而,病变持续存在或复发率低于先前报道(初次手术后总体成功率为82%)。