来自法国的2个家庭中出现的1型痢疾志贺氏菌腹泻合并溶血尿毒综合征的儿科病例群。
A pediatric cluster of Shigella dysenteriae serotype 1 diarrhea with hemolytic uremic syndrome in 2 families from France.
作者信息
Houdouin Véronique, Doit Catherine, Mariani P, Brahimi Naïma, Loirat Chantal, Bourrillon Antoine, Bingen Edouard
机构信息
Services de Microbiologie, Hôpital Robert Debré, Paris, France.
出版信息
Clin Infect Dis. 2004 May 1;38(9):e96-9. doi: 10.1086/383474. Epub 2004 Apr 15.
We report a cluster of pediatric diarrhea due to Shigella dysenteriae serotype 1 involving 11 children in France, including the index case, who had returned from Senegal. Child-to-child transmission was documented by ribotyping. Five children developed hemolytic uremic syndrome (HUS). On the basis of our findings, the choice of antimicrobial treatment for infections with S. dysenteriae serotype 1 should take into account widespread drug resistance and the risk of HUS.
我们报告了法国一起由1型痢疾志贺菌引起的小儿腹泻聚集性病例，涉及11名儿童，包括首例病例，该病例是从塞内加尔返回的。通过核糖体分型记录了儿童之间的传播。5名儿童发展为溶血尿毒综合征（HUS）。根据我们的研究结果，对于1型痢疾志贺菌感染的抗菌治疗选择应考虑广泛的耐药性和HUS风险。
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