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RTCGD: retroviral tagged cancer gene database.
Nucleic Acids Res. 2004 Jan 1;32(Database issue):D523-7. doi: 10.1093/nar/gkh013.
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Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2.
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Targets of the transcriptional repressor oncoprotein Gfi-1.
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The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymus.
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Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors.
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Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment.
J Immunol. 2003 Mar 1;170(5):2356-66. doi: 10.4049/jimmunol.170.5.2356.
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Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation.
Immunity. 2003 Jan;18(1):109-20. doi: 10.1016/s1074-7613(02)00501-0.
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The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival.
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High levels of the onco-protein Gfi-1 accelerate T-cell proliferation and inhibit activation induced T-cell death in Jurkat T-cells.
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The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages.
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