Van Riper Marcia, McKinnon Wendy C
School of Nursing, Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Carrington Hall CB #7460, Chapel Hill, NC 27599, USA.
J Midwifery Womens Health. 2004 May-Jun;49(3):210-9. doi: 10.1016/j.jmwh.2004.01.021.
The purpose of this article is to provide an overview of current knowledge concerning genetic testing for breast and ovarian cancer susceptibility. This overview includes 1) a brief history of genetic testing for breast and ovarian cancer susceptibility, 2) a review of factors that midwives and other health care providers need to consider before offering this type of testing to their clients, 3) management options for clients at high risk for hereditary breast and ovarian cancers, and 4) a discussion of preliminary findings from an ongoing study concerning the family experience of genetic testing, which illustrates some of the ethical issues that emerge for individuals and families during the family experience of genetic testing for breast and ovarian cancer susceptibility.
本文旨在概述目前关于乳腺癌和卵巢癌易感性基因检测的知识。该概述包括：1）乳腺癌和卵巢癌易感性基因检测的简史；2）助产士和其他医疗服务提供者在为客户提供此类检测之前需要考虑的因素回顾；3）遗传性乳腺癌和卵巢癌高危客户的管理选择；4）一项正在进行的关于基因检测家庭体验的研究的初步结果讨论，该研究说明了在乳腺癌和卵巢癌易感性基因检测的家庭体验过程中，个人和家庭出现的一些伦理问题。
