曾接种疫苗的马匹对东部和西部马脑炎疫苗接种的血清学反应。

Serologic responses to eastern and western equine encephalomyelitis vaccination in previously vaccinated horses.

作者信息

Waldridge Bryan M, Wenzel James G W, Ellis A C, Rowe-Morton Sarah E, Bridges E Ricardo, D'Andrea George, Wint Rennia

机构信息

Department of Clinical Sciences, School of Veterinary Medicine, Tuskegee, AL 36088, USA.

出版信息

Vet Ther. 2003 Fall;4(3):242-8.

PMID:15136985

Abstract

A prospective study was performed to determine the serologic response of previously vaccinated horses to revaccination against eastern and western equine encephalomyelitis (EEE and WEE). Horses responded variably to each antigen, and some horses had low or undetectable antibodies 6 months after vaccination. Some horses did not develop increasing titers to EEE or WEE despite recent vaccination. Geometric mean titers peaked 2 weeks after revaccination and were significantly increased from before revaccination. Except for one horse, EEE:WEE titer ratios ranged from 0.25 to 2.0. Regular vaccination against EEE and WEE did not interfere with testing for Saint Louis encephalitis.

摘要

进行了一项前瞻性研究，以确定先前接种过疫苗的马匹再次接种针对东部和西部马脑脊髓炎（EEE和WEE）疫苗后的血清学反应。马匹对每种抗原的反应各不相同，一些马匹在接种疫苗6个月后抗体水平较低或检测不到。一些马匹尽管最近接种了疫苗，但对EEE或WEE的滴度并未升高。几何平均滴度在再次接种后2周达到峰值，且显著高于再次接种前。除一匹马外，EEE:WEE滴度比值在0.25至2.0之间。定期接种EEE和WEE疫苗不影响圣路易斯脑炎的检测。