泰国消化不良患者中用于检测抗幽门螺杆菌抗体的商用免疫测定法评估
Evaluation of commercial immunoassays for detection of antibody against Helicobacter pylori in Thai dyspeptic patients.
作者信息
Hanvivatvong Orrawadee, Pongpanich Atinop, Thong-Ngam Duangporn, Thammacharoenrach Niramol, Kullavanijaya Pinit
机构信息
Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
出版信息
Clin Diagn Lab Immunol. 2004 May;11(3):618-20. doi: 10.1128/CDLI.11.3.618-620.2004.
The performance of five immunoassays for detection of immunoglobulin G antibody against Helicobacter pylori in 191 dyspeptic patients was evaluated. The sensitivities, specificities, accuracies, positive predictive values, and negative predictive values ranged from 86.32 to 97.89%, 57.95 to 72.22%, 77.02 to 83.76%, 71.54 to 77.42%, and 83.33 to 96.23%, respectively. The immunoglobulin A test kit also gave a high sensitivity and negative predictive value (95.79 and 91.40%, respectively), while the specificity was relatively low (51.14%).
对191例消化不良患者进行了5种免疫测定法检测抗幽门螺杆菌免疫球蛋白G抗体的性能评估。其灵敏度、特异性、准确性、阳性预测值和阴性预测值分别为86.32%至97.89%、57.95%至72.22%、77.02%至83.76%、71.54%至77.42%以及83.33%至96.23%。免疫球蛋白A检测试剂盒也具有较高的灵敏度和阴性预测值（分别为95.79%和91.40%），而特异性相对较低（51.14%）。
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