Al-Saghir Abdullah H, Al-Mobeireek Abdullah F
Pulmonary Section, Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia.
Saudi Med J. 2004 May;25(5):557-65.
Bronchiolitis obliterans with organizing pneumonia (BOOP) is now established as a distinct clinicopathologic entity, yet it may be overlooked by clinicians due to unfamiliarity and its non-specific presentation. It can be either idiopathic or associated with a variety of causes, such as infections, drugs, radiation or connective tissue diseases. A lung biopsy is needed to provide histopathologic confirmation. Usually prognosis is good, and the response to steroids may be dramatic, but occasionally BOOP may be fatal or runs a chronic relapsing course. This article is an updated review on current knowledge regarding BOOP.
闭塞性细支气管炎伴机化性肺炎(BOOP)现已被确认为一种独特的临床病理实体,但由于临床医生对其不熟悉以及其表现不具有特异性,它可能会被忽视。它可以是特发性的,也可与多种病因相关,如感染、药物、辐射或结缔组织病。需要进行肺活检以提供组织病理学确诊依据。通常预后良好,对类固醇治疗的反应可能很显著,但BOOP偶尔也可能是致命的,或者呈慢性复发病程。本文是关于BOOP现有知识的最新综述。