Carrié D
Service de cardiologie, CHU Purpan, place du Docteur-Baylac, 31403 Toulouse, France.
Pathol Biol (Paris). 2004 May;52(4):223-7. doi: 10.1016/j.patbio.2004.01.009.
Significant results obtained with coated stents in "de novo" coronary lesion treatment, particularly in complex lesions, have substituted brachytherapy indications. However, curitherapy results in diffuse or proliferative in-stent restenosis treatment show a significant reduction (30-50%) of restenosis and major adverse cardiac events. So, without sufficient scientific proofs with active stents in this indication, curitherapy is the only validated and authorized treatment of second diffuse or proliferative in-stent restenosis.
在“初发”冠状动脉病变治疗中,尤其是在复杂病变中,涂层支架取得的显著成果已取代了近距离放射治疗的适应症。然而,在弥漫性或增殖性支架内再狭窄治疗中,放射治疗使再狭窄和主要不良心脏事件显著减少(30%-50%)。因此,鉴于在该适应症中使用活性支架缺乏充分的科学证据,放射治疗是唯一经过验证和批准用于治疗第二次弥漫性或增殖性支架内再狭窄的方法。