癫痫源性中央前回周围病变切除术前感觉运动皮层的多模态功能图谱。

Multimodal functional mapping of sensorimotor cortex prior to resection of an epileptogenic perirolandic lesion.

作者信息

Kirsch Heidi E, Sepkuty Jehuda P, Crone Nathan E

机构信息

Department of Neurology, University of California San Francisco School of Medicine, San Francisco, CA, USA.

出版信息

Epilepsy Behav. 2004 Jun;5(3):407-10. doi: 10.1016/j.yebeh.2004.02.001.

DOI:10.1016/j.yebeh.2004.02.001

PMID:15145312

Abstract

The effects of chronic epileptogenic lesions on functional anatomy are under debate. Our recent experience during mapping and resection of a lesion in sensorimotor cortex supports the idea that epileptogenic lesions may prompt development of alternate cortical motor representations. Multimodal mapping may uncover alternate areas of functionality that make surgery feasible even when conventional neuroanatomy suggests otherwise. Newer methods such as electrocorticographic spectral analysis may complement traditional electrical cortical stimulation mapping.

摘要

慢性致痫性病变对功能解剖学的影响仍存在争议。我们最近在对感觉运动皮层的一个病变进行定位和切除时的经验支持了这样一种观点，即致痫性病变可能促使替代性皮质运动表征的形成。多模态定位可能会发现其他功能区域，即使传统神经解剖学显示情况并非如此，这些区域也能使手术可行。诸如皮质脑电图频谱分析等更新的方法可能会补充传统的皮质电刺激定位。