Abadco D L, Amaro-Galvez R, Rao M, Steiner P
Division of Pediatric Pulmonology, Children's Medical Center of Brooklyn, NY.
Am J Dis Child. 1992 Sep;146(9):1056-9. doi: 10.1001/archpedi.1992.02160210058021.
To report our experience with flexible fiberoptic bronchoscopy with bronchoalveolar lavage in children with the acquired immunodeficiency syndrome and acute lower respiratory tract disease.
Retrospective study.
Children's Medical Center of Brooklyn, NY, a tertiary-level inner-city hospital.
Eighty-five children with acquired immunodeficiency syndrome and acute lower respiratory tract disease.
One hundred five flexible fiberoptic bronchoscopies with bronchoalveolar lavages.
MEASUREMENTS/MAIN RESULTS: Infective agents were recovered in 88 procedures (84%). Potentially pathogenic bacteria were identified in 56 (56.6%) of 99 procedures. Viruses were found in 28 (29%) of 96 lavages, and fungi in 37 (41.6%) of 89 specimens. Pneumocystis carinii was identified in 22 (22.2%) of 99 specimens. Mycobacteria were isolated from 14 (14%) of 100 specimens. A serious complication occurred in only one procedure (0.95%).
Flexible fiberoptic bronchoscopy with bronchoalveolar lavage is a safe and effective diagnostic procedure that identified infective agents in 80% of children with acquired immunodeficiency syndrome and concomitant acute lower respiratory tract disease.
报告我们在对获得性免疫缺陷综合征合并急性下呼吸道疾病患儿进行纤维支气管镜检查及支气管肺泡灌洗的经验。
回顾性研究。
纽约布鲁克林儿童医疗中心，一家位于市中心的三级医院。
85例获得性免疫缺陷综合征合并急性下呼吸道疾病的患儿。
进行105次纤维支气管镜检查及支气管肺泡灌洗。
测量指标/主要结果：在88次操作（84%）中发现了感染病原体。在99次操作中的56次（56.6%）中鉴定出潜在致病细菌。在96次灌洗中的28次（29%）中发现病毒，在89份标本中的37次（41.6%）中发现真菌。在99份标本中的22次（22.2%）中鉴定出卡氏肺孢子虫。在100份标本中的14次（14%）中分离出分枝杆菌。仅在1次操作（0.95%）中发生了严重并发症。
纤维支气管镜检查及支气管肺泡灌洗是一种安全有效的诊断方法，可在80%的获得性免疫缺陷综合征合并急性下呼吸道疾病患儿中发现感染病原体。
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