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基于神经网络和逻辑回归的糖尿病患者颈动脉狭窄分类

Classification of carotid artery stenosis of patients with diabetes by neural network and logistic regression.

作者信息

Ergün U Uçman, Serhatlioğlu Selami, Hardalaç Firat, Güler Inan

机构信息

Department of Electric and Electronic Engineering, Faculty of Engineering, Afyon Kocatepe University, Afyon, Turkey.

出版信息

Comput Biol Med. 2004 Jul;34(5):389-405. doi: 10.1016/S0010-4825(03)00085-4.

Abstract

The blood flow hemodynamics of carotid arteries were obtained from carotid arteries of 168 individuals with diabetes using the 7.5 MHz ultrasound Doppler M-unit. Fast Fourier Transform (FFT) methods were used for feature extraction from the Doppler signals on the time-frequency domain. The parameters, obtained from the Doppler sonograms, were applied to the mathematical models that were constituted to analyze the effect of diabetes on internal carotid artery (ICA) stenosis. In this study, two different mathematical models such as the traditional statistical method based on logistic regression and a Multi-Layer Perceptron (MLP) neural network were used to classify the Doppler parameters. The correct classification of these data was performed by an expert radiologist using angiograpy before they were executed by logistic regression and MLP neural networks. We classified the carotid artery stenosis into two categories such as non-stenosis and stenosis and we achieved similar results (correctly classified (CC) = 92.8%) in both mathematical models. But, as the degree of stenosis had been increased to 4 (0-39%, 40-59%, 60-79% and 80-99% diameter stenosis), it was found that the neural network (CC = 73.9%) became more efficient than the logistic regression analysis (CC = 67.7%). These outcomes indicate that the Doppler sonograms taken from the carotid arteries may be classified successfully by neural network.

摘要

使用7.5兆赫超声多普勒M型仪,从168名糖尿病患者的颈动脉获取血流动力学数据。采用快速傅里叶变换(FFT)方法在时频域从多普勒信号中提取特征。从多普勒超声图获得的参数应用于构建的数学模型,以分析糖尿病对颈内动脉(ICA)狭窄的影响。在本研究中,使用了两种不同的数学模型,如基于逻辑回归的传统统计方法和多层感知器(MLP)神经网络,对多普勒参数进行分类。在通过逻辑回归和MLP神经网络执行这些数据之前,由专业放射科医生使用血管造影术对这些数据进行正确分类。我们将颈动脉狭窄分为无狭窄和狭窄两类,在两种数学模型中均取得了相似的结果(正确分类率(CC)=92.8%)。但是,当狭窄程度增加到4级(直径狭窄0 - 39%、40 - 59%、60 - 79%和80 - 99%)时,发现神经网络(CC = 73.9%)比逻辑回归分析(CC = 67.7%)更有效。这些结果表明,从颈动脉获取的多普勒超声图可以通过神经网络成功分类。

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