García-Bargo M D, Martí-Fàbregas J, Belvís R, Castaño C, Cocho D, Marín B, Martí-Vilalta J L
Servicio de Neurología, Unidad de Neurorradiología Intervencionista, Hospital de la Santa Creu i Sant Pau, Barcelona.
Neurologia. 2004 Jun;19(5):273-6.
Intracerebral hemorrhage (ICH) by hyperperfusion after carotid angioplasty has a frequency of 1.2 % - 4.4% in the literature. Until now no case of ICH after carotid angioplasty in a tandem lesion has been reported. We present the case of a patient who suffered an ICH due to the hyperperfusion syndrome, after carotid angioplasty of two stenotic lesions of the left internal carotid artery (ICA) (intracranial and extracranial). He was a 58 year old man who suffered repetitive left carotid TIA despite being treated with antiplatelet therapy. An angiogram showed 76 % extracranial stenosis and 96 % intracranial stenosis of the left ICA as well as 59 % extracranial stenosis of right ICA. Angioplasty with stenting of the two stenosis of the left ICA was performed. After 48 hours of the angioplasty, the patient presented a massive ICH and died a few hours later. ICH by hyperperfusion is an infrequent complication of the carotid angioplasty. The risk factors of the ICH should be evaluated in order to decrease their incidence as well as to maintain an intensive control of the arterial pressure during and after the procedure. This case is the first one published after angioplasty of a tandem lesion. It is possible that the pathophysiologic mechanism involved was an excessively rapid restitution of the normal arterial size.
在文献中,颈动脉血管成形术后因高灌注导致的脑出血发生率为1.2% - 4.4%。迄今为止,尚未有串联病变患者在颈动脉血管成形术后发生脑出血的病例报道。我们报告一例患者,在对左侧颈内动脉(ICA)的两个狭窄病变(颅内和颅外)进行颈动脉血管成形术后,因高灌注综合征发生了脑出血。患者为一名58岁男性,尽管接受了抗血小板治疗,但仍反复出现左侧颈动脉短暂性脑缺血发作(TIA)。血管造影显示左侧ICA颅外狭窄76%、颅内狭窄96%,右侧ICA颅外狭窄59%。对左侧ICA的两个狭窄病变进行了血管成形术并置入支架。血管成形术后48小时,患者出现大量脑出血,数小时后死亡。高灌注导致的脑出血是颈动脉血管成形术罕见的并发症。应评估脑出血的危险因素,以降低其发生率,并在手术期间及术后对动脉血压进行强化控制。该病例是串联病变血管成形术后首例发表的病例。所涉及的病理生理机制可能是正常动脉大小恢复过快。