Campo Angora M, García Rodríguez P, Martínez Díaz C, Serrano Garrote O, Herreros de Tejada y López Coterilla A
Servicio de Farmacia, Hospital 12 de Octubre, Madrid.
Farm Hosp. 2004 Mar-Apr;28(2):84-9.
To analyze the use of various maintenance fluid therapy regimens, as well as their adequacy to hospital recommendations, in adult in-patients admitted to a general surgery ward during 1 year.
Data on solution type and volume, fluid therapy regimen, and duration in days were retrospectively collected for each administered solution from computerized medical orders within the Unit-Dose Drug Distribution Area. A database was developed including the composition of available solutions within our hospital, so that electrolytes, glucose and volumes administered may be calculated.
Out of 354 patients undergoing fluid therapy 125 were selected to receive maintenance regimens. Fluid therapy was administered for more than 5 days in 31% of patients. The most commonly supplied fluids were 5% glucose (43%) and 0.9% saline + 1500 mL of 5% glucose + 60 mEq potassium chloride (CIK). Amongst patients receiving the recommended volume/day (84%) 50% received sodium and potassium more than twice as much the recommended amount, and 70% received glucose amounts not covering minimal daily requirements. Potassium was administered according to recommendations in 85% of patients.
There is an excessive use of 0.9% saline and 5% glucose to the detriment of 1/3 glucosaline and 10% glucose, which translates as an excessive daily sodium and defective daily glucose provision. In our hospital we have recommended maintenance fluid therapy regimens, as well as fluids more appropriate for postoperative electrolyte replacement; however, their use is still deficient.
分析某普通外科病房1年内成年住院患者各种维持性液体治疗方案的使用情况及其与医院推荐方案的符合程度。
从单剂量药品分发区的计算机化医嘱中回顾性收集每种所输注溶液的溶液类型、体积、液体治疗方案及天数等数据。开发了一个数据库,其中包含我院可用溶液的成分,以便计算所输注的电解质、葡萄糖和液体量。
在354例接受液体治疗的患者中,125例被选择接受维持治疗方案。31%的患者接受了超过5天的液体治疗。最常用的液体是5%葡萄糖(43%)和0.9%生理盐水+1500毫升5%葡萄糖+60毫当量氯化钾(CIK)。在接受推荐每日液体量的患者中(84%),50%的患者接受的钠和钾超过推荐量的两倍,70%的患者接受的葡萄糖量未达到每日最低需求量。85%的患者按照推荐剂量补钾。
过量使用0.9%生理盐水和5%葡萄糖,而不利于使用1/3的葡萄糖盐水和10%葡萄糖,这意味着每日钠供应过量而葡萄糖供应不足。我院已推荐维持性液体治疗方案以及更适合术后电解质补充的液体;然而,这些方案的使用仍然不足。