Stewart D, McCaig D, Davie A, Juroszek L, Blackwood L, Findlay N, McCarthy S
School of Pharmacy, The Robert Gordon University, Aberdeen AB10 1GG, Scotland, UK.
J Clin Pharm Ther. 2004 Jun;29(3):273-7. doi: 10.1111/j.1365-2710.2004.00555.x.
The role of long-term glycaemic control in minimizing long-term complications of diabetes mellitus is evidence-based and national guidelines recommend a target glycosylated haemoglobin level of approximately 7%. Although the role of self-monitoring blood and urine glucose is less well defined, this activity consumes vast National Health Service (NHS) resources.
The aims of this study were to (i) determine the current practice of glucose self-monitoring in primary care, (ii) determine any changes to therapy made as a result and (iii) compare monitoring and frequency of monitoring in those patients using insulin with those patients taking oral hypoglycaemic agents.
Postal questionnaire to 311 patients using insulin or oral hypoglycaemic agents identified from three general practices.
The response rate was 59.8% (186/311), with the majority of responding patients (n = 158, 87.3%) performing self-monitoring. The patients using insulin were more likely to be self-monitoring than those taking oral therapy (chi(2), P < 0.001, d.f. = 1). The majority of patients who self-monitored and were using insulin (n = 45, 61.1%) altered the dose of insulin if a reading was beyond their target range. However, the majority of patients who self-monitored and were taking oral therapy (n = 48, 68.6%) took no action at all.
Blood glucose self-monitoring was common in those treated with insulin or oral hypoglycaemics, although those using insulin were more likely to self-monitor. Notably many patients, particularly those on oral therapy, took no action based on the results of self-monitoring.
长期血糖控制在将糖尿病长期并发症降至最低方面的作用有循证依据,国家指南建议糖化血红蛋白目标水平约为7%。尽管自我监测血糖和尿糖的作用尚不明确,但这项活动消耗了大量国民医疗服务体系(NHS)资源。
本研究的目的是:(i)确定基层医疗中血糖自我监测的当前做法;(ii)确定由此导致的治疗方面的任何变化;(iii)比较使用胰岛素的患者与口服降糖药的患者的监测情况及监测频率。
对从三家全科诊所中识别出的311名使用胰岛素或口服降糖药的患者进行邮寄问卷调查。
回复率为59.8%(186/311),大多数回复患者(n = 158,87.3%)进行自我监测。使用胰岛素的患者比接受口服治疗的患者更有可能进行自我监测(卡方检验,P < 0.001,自由度 = 1)。大多数进行自我监测且使用胰岛素的患者(n = 45,61.1%)如果读数超出目标范围会改变胰岛素剂量。然而,大多数进行自我监测且接受口服治疗的患者(n = 48,68.6%)根本不采取任何行动。
血糖自我监测在接受胰岛素或口服降糖药治疗的患者中很常见,尽管使用胰岛素的患者更有可能进行自我监测。值得注意的是,许多患者,尤其是接受口服治疗的患者,并未根据自我监测结果采取行动。