库欣综合征患者合并肾上腺腺瘤和肾上腺髓质脂肪瘤：病例报告及文献复习

Combined adrenal adenoma and myelolipoma in a patient with Cushing's syndrome: case report and review of the literature.

作者信息

Hisamatsu Hiroshi, Sakai Hideki, Tsuda Satoshi, Shigematsu Kazuto, Kanetake Hiroshi

机构信息

Department of Urology, Nagasaki University School of Medicine, Nagasaki, Japan.

出版信息

Int J Urol. 2004 Jun;11(6):416-8. doi: 10.1111/j.1442-2042.2004.00815.x.

DOI:10.1111/j.1442-2042.2004.00815.x

PMID:15157212

Abstract

Myelolipoma is an uncommon benign tumor of unknown etiology and adrenal myelolipoma is rarely associated with endocrine disorders. We report a 67-year-old woman with Cushing's syndrome due to left adrenal adenoma associated with myelolipoma. The patient underwent laparoscopic left adrenalectomy and pathological examination revealed an adrenocortical adenoma associated with myelolipoma. To the best of our knowledge, 25 cases of endocrine dysfunction associated with myelolipoma have been reported in the English and Japanese literature. We review and discuss the pathogenesis of adrenal myelolipoma.

摘要

肾上腺髓质脂肪瘤是一种病因不明的罕见良性肿瘤，肾上腺髓质脂肪瘤很少与内分泌紊乱相关。我们报告一例67岁因左肾上腺腺瘤合并肾上腺髓质脂肪瘤导致库欣综合征的女性患者。该患者接受了腹腔镜下左肾上腺切除术，病理检查显示为肾上腺皮质腺瘤合并肾上腺髓质脂肪瘤。据我们所知，英文和日文文献中已报道25例与肾上腺髓质脂肪瘤相关的内分泌功能障碍病例。我们对肾上腺髓质脂肪瘤的发病机制进行综述和讨论。