Du H, Clarke A E, Bacic A
Waksman Institute, PO Box 759 Piscataway, NJ 08855-0759, USA.
Trends Cell Biol. 1996 Nov;6(11):411-4. doi: 10.1016/s0962-8924(96)20036-4.
Arabinogalactanproteins (AGPs) are proteoglycans of the extracellular matrix o f most plants. Since the late 1980s, AGPs have attracted widespread attention from plant biologists following reports of their involvement in plant development. In particular, the use of monoclonal antibodies to carbohydrate epitopes of AGPs has demonstrated stage- and tissue-specificity and has led to suggestions that they are involved in tissue morphogenesis. The recent cloning of the genes for several AGP protein backbones allows us to consider new strategies to address their function. Here, we summarize our knowledge of AGPs and consider parallels with animal proteoglycans as a possible framework for future work.
阿拉伯半乳聚糖蛋白(AGPs)是大多数植物细胞外基质中的蛋白聚糖。自20世纪80年代末以来,AGPs因其参与植物发育的报道而受到植物生物学家的广泛关注。特别是,针对AGPs碳水化合物表位的单克隆抗体的应用已证明其具有阶段和组织特异性,并有人提出它们参与组织形态发生。最近几种AGP蛋白骨架基因的克隆使我们能够考虑新的策略来研究其功能。在此,我们总结了我们对AGPs的认识,并将其与动物蛋白聚糖进行比较,作为未来工作的一个可能框架。