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突触蛋白与突触连接的组装

Synaptic proteins and the assembly of synaptic junctions.

作者信息

Garner C C, Kindler S

机构信息

University of Alabama, Neurobiology Research Center, Birmingham, AL 35213-0021, USA.

出版信息

Trends Cell Biol. 1996 Nov;6(11):429-33. doi: 10.1016/s0962-8924(96)10036-2.

Abstract

Synapses are highly specialized contact sites between neurons and their target cells where information in the form of chemical substances travels from a pre- to a postsynaptic cell. In the central nervous system of mammals, most nerve cells are innervated by functionally distinct types of synapses, each requiring a specific set of molecular constituents for proper function. Various molecular players that may be involved in the assembly of synaptic junctions have been identified recently.

摘要

突触是神经元与其靶细胞之间高度特化的接触位点,化学物质形式的信息在此从突触前细胞传递到突触后细胞。在哺乳动物的中枢神经系统中,大多数神经细胞由功能不同类型的突触支配,每种突触都需要一组特定的分子成分才能正常发挥功能。最近已经鉴定出了可能参与突触连接组装的各种分子成分。

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