脂肪细胞生物学与脂肪细胞因子。

Adipocyte biology and adipocytokines.

作者信息

Haque Wasim A, Garg Abhimanyu

机构信息

Division of Nutrition and Metabolic Diseases, Department of Internal Medicine, Center for Human Nutrition, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

出版信息

Clin Lab Med. 2004 Mar;24(1):217-34. doi: 10.1016/j.cll.2004.01.007.

DOI:10.1016/j.cll.2004.01.007

PMID:15157564

Abstract

Adipose tissue actively participates in regulation of food intake, energy expenditure, fuel metabolism, and a variety of other physiologic processes through its endocrine, paracrine, and autocrine secretory products (Table 4). Abnormal synthesis of these secretory products may be related to the pathogenesis of insulin resistance and its complications in patients who have adipose tissue disorders, such as obesity and lipodvstrophies.

摘要

脂肪组织通过其内分泌、旁分泌和自分泌分泌产物，积极参与食物摄入、能量消耗、燃料代谢以及各种其他生理过程的调节（表4）。在患有脂肪组织疾病（如肥胖症和脂肪营养不良）的患者中，这些分泌产物的异常合成可能与胰岛素抵抗及其并发症的发病机制有关。