Chougle A, Narayanaswamy V
Orthopaedic Department, Glan Clwyd Hospital, North Wales LL18 5UJ, UK.
Int J Clin Pract. 2004 Apr;58(4):420-1. doi: 10.1111/j.1368-5031.2004.0040.x.
Infection with Listeria monocytogenes is rare and has been described in prosthetic valves, stent grafts and prosthetic joints. The route of infection appears to be haematogenous. The choice between conservative treatment with antibiotics or surgical treatment with debridement and revision of the components remains controversial. The best antibiotic treatment is not known with ampicillin being the first choice in most cases. Prosthetic infections with Listeria monocytogenes usually occur in patients with malignancy, diabetes mellitus, chronic renal disease, liver disease, elderly patients and patients receiving immunosuppressive therapy. The hip is the commonest prosthetic joint affected followed by the knee. We report the seventh case of Listeria monocytogenes infection in a non-immunocompromised patient involving a prosthetic joint.
单核细胞增生李斯特菌感染较为罕见,已在人工瓣膜、支架移植物和人工关节中有所报道。感染途径似乎为血行性。在使用抗生素进行保守治疗或通过清创及更换部件进行手术治疗之间的选择仍存在争议。最佳抗生素治疗方案尚不清楚,大多数情况下首选氨苄西林。单核细胞增生李斯特菌引起的人工假体感染通常发生在患有恶性肿瘤、糖尿病、慢性肾病、肝病的患者、老年患者以及接受免疫抑制治疗的患者中。髋关节是最常受影响的人工关节,其次是膝关节。我们报告了第7例非免疫功能低下患者发生的涉及人工关节的单核细胞增生李斯特菌感染病例。