Allerberger F, Kasten M J, Cockerill F R, Krismer M, Dierich M P
Federal Public Health Laboratory, University of Innsbruck, Austria.
Int Orthop. 1992;16(3):237-9. doi: 10.1007/BF00182702.
Listeria monocytogenes is increasingly recognised as a cause of prosthetic joint infection. These infections tend to be more insidious and indolent in contrast to similar infections with Staphylococcus aureus. They can occur in patients who are immunocompromised due to malignancy or other illness or in nonimmunocompromised elderly patients. Listeria infections should not be treated with cephalosporins and prolonged antimicrobial treatment is generally advised for prosthetic joint infections. We noted a high affinity of L. monocytogenes for foreign bodies. Three of twenty-seven cases 11%) of listeriosis under the period of investigation were associated with foreign bodies (hip prosthesis, knee prosthesis and arterial graft).
单核细胞增生李斯特菌越来越被认为是人工关节感染的病因。与金黄色葡萄球菌引起的类似感染相比，这些感染往往更隐匿、进展更缓慢。它们可发生于因恶性肿瘤或其他疾病而免疫功能低下的患者，或非免疫功能低下的老年患者。李斯特菌感染不应使用头孢菌素治疗，对于人工关节感染，一般建议进行长期抗菌治疗。我们注意到单核细胞增生李斯特菌对异物有高度亲和力。在调查期间的27例李斯特菌病病例中，有3例（11%）与异物（髋关节假体、膝关节假体和动脉移植物）有关。
