Hu Daniel C, Cathro Helen P, Okusa Mark D
Department of Medicine, University of Virginia, Charlottesville, USA.
Am J Med Sci. 2004 May;327(5):278-80. doi: 10.1097/00000441-200405000-00029.
Sjögren syndrome is a systemic autoimmune disease that involves the kidney as well as other organs. Tubulointerstitial nephritis secondary to monocyte, lymphocyte, and plasma cell infiltration is the characteristic lesion. The authors report a case of Sjögren related acute interstitial nephritis (AIN) with prominent neutrophilic infiltration in the interstitium. This is the first case describing predominance of neutrophilic infiltration in AIN associated with Sjögren syndrome.
干燥综合征是一种累及肾脏及其他器官的系统性自身免疫性疾病。继发于单核细胞、淋巴细胞和浆细胞浸润的肾小管间质性肾炎是其特征性病变。作者报告了一例干燥综合征相关的急性间质性肾炎（AIN）病例，其间质中有显著的中性粒细胞浸润。这是首例描述干燥综合征相关AIN中以中性粒细胞浸润为主的病例。
