Olvera-Cortés Esther, Guevara Miguel Angel, González-Burgos Ignacio
Laboratorio de Neurofisiología Experimental, Centro de Investigación Biomédica de Michoacán, Instituto Mexicano del Seguro Social, AP 7-70, CP 58261 Morelia, Mich., Mexico.
Brain Res Bull. 2004 Feb 1;62(5):379-84. doi: 10.1016/j.brainresbull.2003.10.003.
The change in the percentage of rat hippocampal high-frequency theta activity from being immobile and awake to swimming behaviour was calculated for three groups of rats, trained in either place learning, cue learning or egocentric learning in the Morris water maze. The place-learning-trained rats showed an increase in the percentage of theta activity, along with a significant reduction in escape latency over the last 3 days of training. No changes were observed in the other two groups. Because the motor activity displayed by the three groups of rats was similar, we suggest that the increase in the percentage of theta activity concomitant with place-learning training could be related to the processing of information by the hippocampus, rather than to the displayed motor activity.
在莫里斯水迷宫中，对三组分别接受位置学习、线索学习或自我中心学习训练的大鼠，计算其从静止清醒状态到游泳行为时海马高频θ活动百分比的变化。接受位置学习训练的大鼠在训练的最后3天，θ活动百分比增加，同时逃避潜伏期显著缩短。其他两组未观察到变化。由于三组大鼠表现出的运动活动相似，我们认为位置学习训练伴随的θ活动百分比增加可能与海马体对信息的处理有关，而非与所表现出的运动活动有关。
