Traub-Dargatz J L, Schultheiss P C, Kiper M L, Stashak T S, Wrigley R, Schlipf J, Applehans F M
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
J Am Vet Med Assoc. 1992 Aug 15;201(4):603-7.
Fibrosis of the small intestine led to recurrent colic and weight loss in 2 ponies and 5 horses. There was a reduction in the length of the small intestine to one-half normal in horses 4 to 7. Histologic examination revealed substantial small intestinal submucosal fibrosis and arteriole sclerosis. The cause was not determined, but an environmental factor was suspected because 3 horses were from the same farm and the other animals were from within a 10-mile radius of the farm. The submucosal fibrosis appeared to be secondary to sclerosis of arterioles in the submucosa and mesentery, with low blood flow state or altered vessel permeability.
小肠纤维化导致2匹矮种马和5匹马反复出现绞痛和体重减轻。4至7号马的小肠长度缩短至正常长度的一半。组织学检查显示小肠黏膜下大量纤维化和小动脉硬化。病因未明，但怀疑是环境因素，因为有3匹马来自同一个农场，其他动物来自该农场半径10英里范围内。黏膜下纤维化似乎继发于黏膜下层和肠系膜小动脉的硬化，伴有低血流状态或血管通透性改变。
