二十分钟与四十五分钟早晨强光治疗对老年受试者入睡性失眠的影响

Twenty minutes versus forty-five minutes morning bright light treatment on sleep onset insomnia in elderly subjects.

作者信息

Kirisoglu C, Guilleminault C

机构信息

Stanford University Sleep Disorders Clinic, 401 Quarry Road, Suite 3301, Stanford, CA 94305, USA.

出版信息

J Psychosom Res. 2004 May;56(5):537-42. doi: 10.1016/j.jpsychores.2004.02.005.

DOI:10.1016/j.jpsychores.2004.02.005

PMID:15172210

Abstract

OBJECTIVE

To compare the efficacy of 20 min versus 45 min light exposure for relieving psychophysiological insomnia in the elderly.

METHODS

Prospective recruitment of subjects 60 years and older with psychophysiological insomnia. Random distribution to 20 or 45 min of daily exposure to 10,000 lux for 60 days. Sleep latency, total sleep time, fatigue and activity were measured at baseline and 3 and 6 months posttreatment. Blind analysis of data and comparison were performed using repeated-measure analysis of variance, independent samples t test and Wilcoxon rank signed test.

RESULTS

At 3 months, improvement was significantly higher in the 45-min versus 20-min condition. At 6 months, variables returned toward baseline in the 20-min but not in the 45-min condition.

CONCLUSIONS

Twenty minutes of bright light treatment leads to a lesser treatment response than 45 min at 3-month follow-up and to a return toward baseline at 6-month follow-up that was not seen with a 45-min exposure.

摘要

目的

比较20分钟与45分钟光照对缓解老年人心理生理性失眠的疗效。

方法

前瞻性招募60岁及以上患有心理生理性失眠的受试者。随机分为两组，一组每天接受20分钟10000勒克斯的光照，另一组每天接受45分钟10000勒克斯的光照，持续60天。在基线、治疗后3个月和6个月时测量睡眠潜伏期、总睡眠时间、疲劳程度和活动情况。采用重复测量方差分析、独立样本t检验和Wilcoxon秩和检验对数据进行盲法分析和比较。