Olakowski Marek, Lampe Pawel, Musiewicz Marcin, Swiatkowska-Szlachta Ewa
Wiad Lek. 2004;57(1-2):25-8.
Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. From January 1998 to December 2000 in the Department od Digestive Tract Surgery 294 patients were operated on neoplasms of the stomach. In 12 patients (4%) gastric mesenchymal tumor was diagnosed (GMT) (9 W, 3 M). Median age was 50 years (15-71). All patients with diagnosis of tumor in the abdominal cavity underwent operation. Median diameter of tumor was 6 cm (2-28). We performed following operations: total gastric resection--1, partial gastric resection--2, wedge gastric resection--9. Postoperative complications occurred in 3 patients (25%). No hospital deaths were observed. In all cases diagnosis was established during or after operation based on histopathological examination of resected tumor. In 10 patients GIST was diagnosed and in 2--schwannoma. Follow-up has lasted for 12-48 months. At the present among 12 patients 11 (92%) are alive without recurrence of the disease. In 1 patient recurrence occurred after 18 months postoperatively which caused his death.
Gastric mesenchymal tumors are diagnosed mostly during or after operation based on histopathological examination of resected tumor. Extent of gastric resection does not influence results of treatment in benign neoplasms.
胃肠道间质瘤(GIST)是胃肠道最常见的间叶组织肿瘤。1998年1月至2000年12月期间,在消化道外科有294例患者接受了胃部肿瘤手术。其中12例(4%)被诊断为胃间叶组织肿瘤(GMT)(9例女性,3例男性)。中位年龄为50岁(15 - 71岁)。所有被诊断为腹腔肿瘤的患者均接受了手术。肿瘤的中位直径为6厘米(2 - 28厘米)。我们实施了以下手术:全胃切除术1例、部分胃切除术2例、胃楔形切除术9例。3例患者(25%)出现术后并发症。未观察到医院死亡病例。所有病例均在手术期间或术后根据切除肿瘤的组织病理学检查确诊。10例诊断为GIST,2例为神经鞘瘤。随访持续了12 - 48个月。目前,12例患者中有11例(92%)存活且无疾病复发。1例患者术后18个月出现复发并导致死亡。
胃间叶组织肿瘤大多在手术期间或术后根据切除肿瘤的组织病理学检查确诊。胃切除范围对良性肿瘤的治疗结果无影响。