Srivastava Sunil, Taylor Perdita, Wood Lauren V, Lee Susan S, Robinson Michael R
National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1863, USA.
Ophthalmic Surg Lasers Imaging. 2004 May-Jun;35(3):254-5.
Although the ganciclovir implant is an effective and well-tolerated treatment for cytomegalovirus retinitis in patients with human immunodeficiency virus infection, complications that may occur include retinal detachment, implant extrusion, and endophthalmitis. A 22-year-old woman with human immunodeficiency virus infection presented with a painful left eye with scleritis overlying previous ganciclovir implant sclerotomy sites. The inflammation progressed 360 degrees around the pars plana with progressive thinning at the implant sites. Post-surgical necrotizing scleritis is another complication that can occur in patients with ganciclovir implants.