Taylor William J, Harrison Andrew A
Wellington Regional Rheumatology Unit, Hutt Valley District Health Board, Lower Hutt, New Zealand.
Arthritis Rheum. 2004 Jun 15;51(3):311-5. doi: 10.1002/art.20421.
To determine whether the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) could be a valid indicator of disease activity in psoriatic arthritis (PsA).
Patients with PsA identified from a disease-register and case-note review answered a questionnaire by mail (n = 133); some patients (n = 86) consented to examination. In a second sample of 47 consecutive clinic attendees with PsA, logistic regression examined the independent contribution of BASDAI to disease activity, as judged by treatment decisions at that time.
BASDAI correlated highly with patient perception of disease activity (r = 0.739) and there was no significant effect of the pattern of disease (axial or peripheral) on this relationship. However, only physician perception of disease activity was significantly associated with high or low disease activity (odds ratio 18.4, 95% confidence interval 2.9-118.3). BASDAI, patient perception, and erythrocyte sedimentation rate failed to contribute significantly to the model.
BASDAI performs similarly for axial and peripheral PsA but does not correlate well with external indicators of disease activity, such as treatment decisions.
确定巴斯强直性脊柱炎疾病活动指数(BASDAI)是否可作为银屑病关节炎(PsA)疾病活动的有效指标。
从疾病登记册和病例记录回顾中识别出的PsA患者通过邮件回答问卷(n = 133);部分患者(n = 86)同意接受检查。在连续就诊的47例PsA患者的第二个样本中,逻辑回归分析了BASDAI对疾病活动的独立贡献,当时通过治疗决策来判断疾病活动。
BASDAI与患者对疾病活动的感知高度相关(r = 0.739),疾病模式(轴向或外周)对这种关系没有显著影响。然而,只有医生对疾病活动的感知与疾病活动的高低显著相关(优势比18.4,95%置信区间2.9 - 118.3)。BASDAI、患者感知和红细胞沉降率对模型的贡献不显著。
BASDAI在轴向和外周PsA中的表现相似,但与疾病活动的外部指标(如治疗决策)相关性不佳。