Agewall Stefan, Berglund Margareta, Henareh Loghman
Department of Cardiology, Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden.
Clin Cardiol. 2004 May;27(5):271-4. doi: 10.1002/clc.4960270506.
Psychosocial factors have been suggested as risk factors for atherosclerotic disease.
The purpose of the present study was to examine whether there is a gender difference in quality of life after a myocardial infarction with modem treatment of acute ischemic heart disease.
In all, 123 men and women aged between 31 and 80 years, and with a hospital-diagnosed myocardial infarction occurring 1-12 months prior to inclusion, were studied. Minor symptoms evaluation profile (MSEP) was used to estimate quality of life at entry.
Age, hemodynamic data, smoking habits, as well as laboratory data, concomitant cardiovascular disease, and revascularization rate did not differ between men and women. Women had significantly more negative feelings regarding all the estimated dimensions of quality of life (Contentment, Vitality, and Sleep) than did men.
Self-assessed quality of life after a myocardial infarction was significantly lower among women than among men despite similar age, treatment, and hemodynamic and laboratory data. The causal relationship is however, not known. Further studies are needed to evaluate the underlying mechanism of this observation. This may lead to the development of novel treatment strategies in female patients after a myocardial infarction.
心理社会因素已被认为是动脉粥样硬化疾病的危险因素。
本研究的目的是探讨在急性缺血性心脏病现代治疗后心肌梗死患者的生活质量是否存在性别差异。
共研究了123名年龄在31至80岁之间、在纳入研究前1至12个月被医院诊断为心肌梗死的男性和女性。使用轻微症状评估量表(MSEP)在入组时评估生活质量。
年龄、血流动力学数据、吸烟习惯以及实验室数据、伴发的心血管疾病和血管重建率在男性和女性之间没有差异。在生活质量的所有评估维度(满意度、活力和睡眠)方面,女性的负面情绪明显多于男性。
尽管年龄、治疗、血流动力学和实验室数据相似,但心肌梗死后女性自我评估的生活质量明显低于男性。然而,因果关系尚不清楚。需要进一步研究以评估这一观察结果的潜在机制。这可能会促使针对心肌梗死后女性患者开发新的治疗策略。