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老年人使用非典型抗精神病药物后的迟发性运动障碍发生率

Tardive dyskinesia rates with atypical antipsychotics in older adults.

作者信息

Jeste Dilip V

机构信息

Division of Geriatric Psychiatry, University of California, San Diego, San Diego, CA, USA.

出版信息

J Clin Psychiatry. 2004;65 Suppl 9:21-4.

Abstract

Tardive dyskinesia is a chronic drug-induced movement disorder that tends to be persistent in older adults who are treated with antipsychotics. Tardive dyskinesia can affect older patients both physically and psychologically, leading to frequent falls, difficulty eating, and depression. While atypical antipsychotics may cause tardive dyskinesia, the percentage is usually significantly lower than with conventional antipsychotics. Using atypical antipsychotics, particularly at lower doses, may aid in preventing symptoms of tardive dyskinesia in older adults.

摘要

迟发性运动障碍是一种慢性药物引起的运动障碍,在接受抗精神病药物治疗的老年人中往往持续存在。迟发性运动障碍会在身体和心理上影响老年患者,导致频繁跌倒、进食困难和抑郁。虽然非典型抗精神病药物可能会引起迟发性运动障碍,但其发生率通常明显低于传统抗精神病药物。使用非典型抗精神病药物,尤其是较低剂量时,可能有助于预防老年人迟发性运动障碍的症状。

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