Verghese S, Maria C F, Mullaseri A S, Asha M, Padmaja P, Padhye A A
Institute of Cardiovascular Diseases, Madras Medical Mission, 4-A, JJ Nagar, Mogappair Chennai, India.
Mycoses. 2004 Jun;47(5-6):252-6. doi: 10.1111/j.1439-0507.2004.00980.x.
Fungal valvular endocarditis is an unusual cause of endocarditis, yet very important because of its historically poor prognosis. We report two fatal cases of fungal valvular endocarditis following cardiovascular surgery, presenting as femoral artery embolism. Aspergillus terreus and A. flavus were the causative agents of endocarditis in the two patients. Diagnosis was established very early by culture of the emboli and was confirmed later by isolation of the same Aspergillus species from the resected valve tissue.
真菌性心内膜炎是心内膜炎的一种罕见病因,但因其历史上预后较差而非常重要。我们报告了两例心血管手术后发生的真菌性心内膜炎致死病例,表现为股动脉栓塞。土曲霉和黄曲霉是这两名患者心内膜炎的病原体。通过栓子培养很早就确立了诊断,后来从切除的瓣膜组织中分离出相同的曲霉菌种进一步证实了诊断。