一名急性髓系白血病患者感染短帚霉

Scopulariopsis brevicaulis infection in a patient with acute myeloid leukemia.

作者信息

Ng K P, Soo-Hoo T S, Na S L, Gan G G, Sangkar J V, Teh A K

机构信息

Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur.

出版信息

Med J Malaysia. 2003 Oct;58(4):608-12.

PMID:15190640

Abstract

Scopulariopsis brevicaulis is a soil fungus normally associated with onychomycosis. It causes subcutaneous infection in immunocompromised patients and is rarely isolated from blood. A case of systemic Scopulariopsis brevicaulis infection was reported in a patient with acute myeloid leukemia. The patient developed persistent fever that did not respond to wide spectrum antibiotics and amphotericin B. Scopulariopsis brevicaulis was the only pathogen isolated from blood cultures. The fever subsided with itraconazole and there was no recurrence of fungal infection with prolonged maintenance of oral itraconazole.

摘要

短帚霉是一种通常与甲癣相关的土壤真菌。它可在免疫功能低下的患者中引起皮下感染，且很少从血液中分离出来。一名急性髓系白血病患者报告了一例系统性短帚霉感染病例。该患者出现持续发热，对广谱抗生素和两性霉素B均无反应。短帚霉是从血培养中分离出的唯一病原体。发热在使用伊曲康唑后消退，且长期口服伊曲康唑维持治疗后真菌感染未复发。